News
54gene Completes Initial Phase of the Landmark Nigerian 100K Genome Project
54gene, the health technology company advancing African genomics research for improved global health outcomes, has through its non-profit initiative, the African Centre for Translational Genetics (ACTG), completed its first consortium-led publication on over 100,000 Nigerians as commissioned in 2020 at its launch.
The Non-Communicable Diseases Genetic Heritage Study (NCD-GHS) consortium has published a paper in the esteemed journal, Nature Genetics, entitled “Promoting the Genomic Revolution in Africa through the Nigerian 100k Genome Project”.
Through 54gene’s ACTG, the consortium operates as a unique public-private partnership involving leading African scientists guided by a team of global genomic leaders as the Scientific Advisory Board to achieve the mission of the ACTG.
The consortium, which is made up of scientists from 54gene, the Nigerian Institute of Medical Research, and the Center for Genomics Research and Innovation at the National Biotechnology Development Agency as well as researchers from multiple academic institutions in Nigeria and London School of Hygiene and Tropical Medicine, is built on a shared vision of positioning African populations to benefit from advances in genomic science.
According to the paper, as of January 2019, approximately 3% of genomic data being used for genome wide association studies (GWAS) came from people of African descent, with this statistic dropping to 1.1% in 2021.
The paper details efforts in building an important resource that could significantly enable African populations to benefit from the global efforts at achieving precision medicine for various diseases.
This has been achieved through the production of a comprehensive catalog of human genetic variation, examining the characteristics of non-communicable diseases (NCDs) in 100,000 adults in Nigeria seeking to understand the genetic basis of the highly prevalent illnesses such as cancers, diabetes, Alzheimer’s, chronic kidney and sickle cell disease, among others.
Non-communicable diseases (NCDs) kill more than 41 million people every year, accounting for 71% of all deaths globally. The prevalence of NCDs is projected to become higher than that of infectious diseases in Africa by 2030.
The study spans the breadth of the Nigerian population with data gathered from the 6 geopolitical zones in the country and sampling from the majority of the more than200 ethnolinguistic groups, with ethically consulted participants being recruited falling under two categories: disease cases recruited from disease specialist clinics, and community cases which are individuals with initially unknown diseases recruited from communities through household surveys.
Dr. Abasi Ene-Obong, 54gene Founder and CEO, said, “Along with our partners, we are proud to be leading the new frontier of African genomics. Precision medicine goes against the one-size-fits-all approach to disease treatment as it is more inclusive, with people treated on their unique genetic makeup.
With more than 200 ethnic groups and 500 different languages, Nigeria has one of the most diverse ethnolinguistic concentrations in the world. This pioneering study from the Nigerian population provides an excellent window into the representation of diversity across Africa.
With recruitment nearly complete and the commencement of data generation and bioinformatics analysis, we are excited at how this study makes the promise of precision medicine more attainable to Nigerians, Africans and the global population.”
Dr. Segun Fatumo, co-lead NCD-GHS and the first author of the landmark paper said, “I am so proud of what NCD-GHS has achieved in only about two years. In our own eyes, 100K genomes of Africa are emerging from more than 300 diverse ethnic groups in Nigeria.
“The current lack of genomic diversity has resulted in significant missed scientific and medical opportunities, but NCD-GHS strategic vision to drive new large-scale studies with rich African genome datasets would help fill some gaps. I am deeply honoured to be a co-lead of this initiative.
“The NCD-GHS’s public-private partnership with 54gene pioneers a model to increase diversity in genomic studies, including capacity building and plan to develop more genomic leaders in Africa.”
Speaking on the publication of the research paper, Colm O’Dushlaine, Vice President, Genomics and Data Science at 54gene, said, “The 100k project supports 54gene’s core mission to equalize precision medicine, by building rich genomic datasets that will be used to generate powerful insights for the benefit of African, and other global populations.
“African populations are among the most diverse in the world. In the context of genome-wide association scans, more variation – more shots on goal – can help to provide new insights into the etiology of disease and drive novel therapeutic target discovery.
“The broader strategic objectives of the NCD-GHS are far-reaching. They include a focus on the creation of genomics leaders in Africa, efforts to increase the number of skilled African genomics scientists to help drive new studies and discoveries, initiatives that drive progressive health policy and practice, and the promotion of discourse and thought leadership on ethical, legal and social issues in genomics research and precision medicine. All of these are central to 54gene’s mission and values.”
Aminu Yakubu, VP Research Governance and Ethics, said, “Building on the legacy of the H3Africa project, the capacity building objective of the NCD-GHS in the 100K Genome Project is a strategic undertaking that would catalyse the future we envisage – of Africans with the skillset and knowledge, able to lead genomic insights generation and development to address health challenges faced by Africans over the long haul.
“It is a people-facing impact creation initiative that puts the social value of the work we do at the center, facilitated through the African Center for Translational Genetics. The focus of one of the NCD-GHS agendas on governance and ethics was deliberate to ensure that we are aligned with existing country-specific and international best practices.
“Our commitment to also support academic thought leadership on ethics and governance issues in genomics research would allow us to evolve as we learn of better ways to protect the welfare of research participants and ensure fairness in research collaborations.”
A former Executive Director at Asset Management Corporation of Nigeria (AMCON), Abbas Muhammed Jega, has shed light on the financial dealings between Arik Air and Union Bank, revealing that the airline’s debt to AMCON was over N100 billion as of 2015 and remained unpaid.
Testifying as the third prosecution witness in the ongoing trial of Ahmed Kuru, former AMCON MD/CEO, and four others, Jega disclosed that AMCON acquired Arik’s loans from Union Bank and Keystone Bank, but not Zenith Bank, which was purchased after his exit.
According to Jega, AMCON discovered in a London meeting that Union Bank had sold them a guarantee rather than a loan, which was meant to cover foreign lenders in case Arik defaulted.
“We invited Arik to resolve the issue with Union Bank, but the arrangement disclosed by me never existed,” Jega said.
Jega attributed Arik’s inability to repay to over-trading, which led to their inability to service existing debts. He revealed that AMCON attempted to restructure Arik’s debt and even offered additional loan facilities to help the airline with working capital problems.
However, Arik failed to meet repayment obligations, prompting AMCON to propose two solutions: a debt equity swap and management control. Both options were rejected or delayed by Arik.
Under cross-examination, Jega confirmed that Kamilu Omokide and Captain Roy Ilegbodu played no role in the loan purchase or London meeting.
The matter has been adjourned to June 30, July 1, and July 2, 2025, for further cross-examination.
The case involves alleged financial misappropriation amounting to N76 billion and $31.5 million, with Ahmed Kuru, Kamilu Omokide, Captain Roy Ilegbodu, Union Bank Ltd, and Super Bravo Ltd as defendants, presided over by Justice Mojisola Dada.
Alhaji Mohammed Idris, Minister of Information and National Orientation is to chair the public presentation of the book Nigeria Media Renaissance: GOCOP Perspective on Online Publishing, a publication of Guild of Corporate Online Publishers (GOCOP). The event is scheduled for 110am on Tuesday June 17, 2025 at the Continental Hotel, Abuja.
President of GOCOP, Maureen Chigbo, who confirmed this development said the book presentation will be graced by eminent personalities from all walks of life, including government officials, captains of industry, media practitioners and other professionals, representatives of international organisations, directors of non-governmental organisations.
Alhaji Idris was sworn in as Minister of Information and National Orientation on August 21, 2023, following his appointment by President Bola Ahmed Tinubu. With over three decades of experience in broadcasting, newspapering, public relations, and advertising, Idris has brought a wealth of expertise to the role.
His academic background includes degrees in English Studies from Uthman Danfodio University, Sokoto, and Bayero University, Kano. As an entrepreneur, he established notable media outlets such as Blueprint, WE FM radio station, and Rapid Television in Abuja.
He is a prominent figure in professional associations such as National Institute of Public Relations, African Public Relations Association, Public Relations Consultants Association of Nigeria, and Newspaper Proprietors Association of Nigeria.
As the founder of Bifocal Communications, a leading public relations and communications consultancy, Idris has served both local and transnational corporations.
Beyond his professional endeavours, Idris is committed to social responsibility through the Mohammed Idris Malagi (MIM) Foundation, which has positively impacted many lives. As a reward for his contributions to the development of his immediate environment and beyond, The Etsu Nupe conferred “Kaakaki Nupe” on him.
A press statement by the GOCOP Publicity Secretary, Ogbuefi Remmy Nweke, quoted the GOCOP president as saying that the proceeds of the book will be used to fund the N2.3 billion GOCOP MEDIA CENTRE, a multi-purpose resource centre comprising a secretariat, a 21st Century library and event halls, among others.
Nweke further noted that the Guild of Corporate Online Publishers (GOCOP) was established to promote professionalism in online publishing, ensuring its members uphold the fundamental principles of journalism.
Comprising seasoned editors and senior journalists with distinguished career in print and electronic media, GOCOP’s membership has traversed the online publishing, recognizing its pivotal role in shaping the future of journalism globally. With 120 corporate publishers as members, GOCOP continues to uphold the highest standards of online journalism.
Advertising Regulatory Council of Nigeria (ARCON) has issued a stern warning to marketers, content creators, and social media influencers amid an alarming rise in fraudulent, AI-generated advertisements circulating across digital platforms.
Dr. Olalekan Fadolapo, director-general, ARCON, during a press briefing at its Lagos headquarters, decried the “porous” state of Nigeria’s online ad ecosystem and pledged to prosecute offenders to the fullest extent of the law.
Dr. Fadolapo opened the media parley by highlighting how easily unscrupulous operators deploy artificial intelligence tools to produce convincing—but entirely fabricated—advertisements.
“Our social media space has become so porous that people now freely post fake adverts, some of which claim outrageous and bogus benefits,” he remarked.
According to the Director-General, these deceptive campaigns often promise “miraculous cures” or “guaranteed returns” without any credible data or verifiable sources to back them.
Among the most alarming examples cited was an herbal remedy advertisement alleging to cure over 200 ailments—ranging from HIV to cancer—through a single “miracle” concoction.
“Imagine an advert claiming that a single herbal drug could cure HIV, cancer, and more than 200 other diseases,” Dr. Fadolapo said.
ARCON’s DG emphasized that such misleading advertisements not only jeopardize public health—by luring vulnerable individuals into purchasing untested or harmful products—but also undermine consumer confidence in legitimate businesses operating within advertising guidelines.
Dr. Fadolapo pointed to the regulatory vacuum that allows bad actors to exploit the anonymity of social media.
Unlike traditional broadcast or print media—where advertisements must pass through editorial or legal vetting—online platforms can be manipulated with minimal oversight.
Creating an ad using AI-powered design and voice generators, he warned, takes only minutes, making it difficult for regulators to identify the original perpetrators.
“The CBEX case is a painful reminder of what can happen when digital platforms are left unchecked,” Dr. Fadolapo said, explaining that the scheme purportedly defrauded unsuspecting Nigerians of nearly $2 trillion through slick, unregulated social media promotions.
He described how the CBEX promoters used AI-generated video testimonials, falsified financial statements, and cloned websites to entice victims with promises of triple-digit returns on cryptocurrency trades.
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