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Good News as Scientists Find Ebola Vaccines

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A pair of experimental Ebola vaccines that protect monkeys from the fatal disease ravaging West Africa have been developed.

According to a new study, the vaccine is effective for at least five weeks in lab monkeys but requires boosting with an additional vaccine to extend its protection to 10 months.

The findings offer a glimpse of which – if any – of the Ebola vaccines in development will prove effective, and in what form.

Pharmaceutical firms are accelerating their efforts to provide Ebola vaccines and treatments as the worst known outbreak of the virus tears through West Africa, killing more than 2,000 people.

The worst known outbreak of the Ebola virus has ravaged West Africa, killing more than 2,000 people.

The results of the new study suggest, for instance, that a vaccine by pharma giant GlaxoSmithKline (GSK) now being tested on healthy volunteers will protect against Ebola infection in the short term, but may have to be augmented for long-term protection.

The study, published in Nature Medicine, is the first to report that a vaccine regimen produced ‘durable immunity’ against Ebola, protecting four out of four monkeys for 10 months.
 
The vaccine uses a chimp adenovirus, closely related to a human version that causes upper respiratory tract infections, into which scientists spliced an Ebola gene.

The adenovirus infects cells in a vaccinated animal, causing them to take up the gene and produce Ebola proteins.

That primes the immune system to attack the proteins of Ebola viruses when an infection occurs

The vaccine in the study is similar to competing vaccines being developed by GSK, which began human safety trials last Tuesday, and by Johnson & Johnson (J&J), which aims to start safety trials in early 2015.

A third experimental Ebola vaccine uses a different delivery system, a livestock pathogen called vesicular stomatitis virus (VSV).

A version developed by the Public Health Agency of Canada and licensed to NewLink Genetics is scheduled to be tested for safety in healthy volunteers this fall.

Profectus BioSciences is also developing a VSV vaccine.

In the new study, led by Nancy Sullivan of the National Institute of Allergy and Infectious Diseases (NIAID), researchers sought to see whether a double dose of vaccine in a regimen called ‘prime-boost’ would address two different clinical needs.

One is protecting against Ebola immediately, said Dr Anthony Fauci, NIAID director as when a person is heading to an area with an Ebola outbreak.

In the study, an adenovirus vaccine essentially the same as GSK’s does so: four of four vaccinated macaque monkeys given otherwise lethal doses of Ebola five weeks later survived and had no detectable virus in their blood. All unvaccinated monkeys died within six days.

The other need is to protect someone whose stay in an Ebola zone lasts months.

Here, the adeno vaccine faltered at one dose: when eight vaccinated macaques were exposed to Ebola 10 months later, six died.

With a new group of macaques, however, the scientists followed the initial adeno vaccine eight weeks later with a booster shot using a different carrier virus, called MVA (modified vaccine Ankara) and carrying the same Ebola gene. This time, all four infected monkeys were still protected at 10 months.

The human trial of the GSK vaccine uses a single adenovirus dose: regulators require safety trials to test each element of a regimen separately, said NIAID’s Fauci, so any adverse events can be traced more easily.

GSK also plans to test a two-dose prime-boost version, said spokeswoman Mary Ann Rhyne.

J&J’s Ebola vaccine consists of an adenovirus prime followed by an MVA boost made by Bavarian Nordic.

‘After the boost, protection is not only stronger but also longer-lasting,’ said J&J spokesman Daniel De Schryver.

Thomas Geisbert of the University of Texas Medical Branch works on the VSV-based Ebola vaccine being developed by Profectus.

He questioned the practicality of a two-shot vaccine regimen.

‘You really need a fast-acting single injection vaccine’ for protecting a community during an outbreak or preparing first responders and healthcare workers, he said.

Only VSV vaccines have been shown to protect lab monkeys when given after infection with Ebola, Geisbert said: ‘This makes it so much more useful than any of the other vaccines. For outbreaks, it works fast.’


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FG Deploy New Printers for Passports following Outcries from Nigerians in Diaspora

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Nigerians in the diaspora have petitioned Dr. Olubunmi Tunji-Ojo, minster of Interior, over passport printing in Atlanta and New York Consulates in the United States of America.

FG Deploy New Printers for Passports following Outcries from Nigerians in Diaspora

To this effect, the minister has approved and directed the Nigeria Immigration Service (NIS) to immediately deploy new printers to the passport offices in both cities.

These printers, according to him, are ready for installation. This short-term solution, he said, aims to resolve the current challenge promptly.

In a statement, the minister said that there is a new solution being implemented as a long-term plan that will usher in a streamlined passport regime, enabling Nigerians to apply for their passports with more ease.

Part of this plan includes the activation of a Passport Personalisation Centre in Abuja, which is scheduled to start in the next few weeks while also opening up more countries for the already-deployed contactless solution.

According to Tunji-Ojo, they are working round the clock, and none of the agencies is left behind.

“At the Nigeria Immigration Service, there has been an end-to-end automation of the passport application process and the introduction of the contactless application process, which has since been launched in Canada,” he said.

 


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CBN’s FX Code to Boost Transparency for Launch on January 28

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The Central Bank of Nigeria (CBN) said it has approved the release of the Nigerian Foreign Exchange (FX) Code and will officially launch the same on January 28, 2025.

The FX code serves as a guideline to the banking industry to promote ethical conduct of authorised dealers in the Nigerian Foreign Exchange Market (NFEM).

“The Bank will formally launch the Code at the CBN Head Office Auditorium, Abuja, on Tuesday, January 28, 2025,” the CBN said in a notice published on its website.

In a bid to strengthen the governance and transparency of Nigeria’s FX market, the CBN in November 2024 introduced revised guidelines for the Nigeria Foreign Exchange Market (NFEM).

A key feature of these guidelines requires the boards of banks, alongside their Chief Executive Officers (CEOs) and Chief Compliance Officers, to annually attest to the Nigeria FX Code of Ethics and Conduct. This attestation underscores their commitment to uphold market integrity and comply with all CBN-issued circulars and guidelines.

The revised guidelines aim to deepen the foreign exchange market following the consolidation of all official FX market windows. The circular, issued by Omolara Omotunde Duke, director of the CBN’s financial markets department, supersedes prior directives, including the operational changes announced on June 14, 2023, and earlier circulars dating back to 2017.

Under the new framework, authorised dealers must facilitate FX transactions for firms and individuals while ensuring compliance with regulations. These dealers are tasked with conducting due diligence, providing transparent pricing, and offering market access through digital solutions.

Furthermore, all legitimate FX transactions must occur exclusively through authorised dealers, while dealings with unlicensed intermediaries are strictly prohibited.

Bureaux de Change (BDC) operators are also included in the revised guidelines. Licensed BDCs are allowed to purchase FX from authorised dealers to meet customer needs, within the limits set by the CBN. Similarly, all FX transactions conducted by BDCs, International Money Transfer Operators (IMTOs), and authorised dealers must adhere to the terms of their licenses and the Nigeria FX Code.


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Visa, Moniepoint Join Forces to Accelerate Financial Inclusion in Africa

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Moniepoint Inc, one of Nigeria’s leading business payments and banking services platforms, has secured an investment from Visa, a global leader in digital payments.

The investment marks an important milestone in Visa’s commitment to advancing financial inclusion and shaping the future of digital payments while fostering SME growth across Africa.

Founded in 2015 by Tosin Eniolorunda and Felix Ike, Moniepoint (formerly known as TeamApt) has established itself as a leading financial platform for Nigeria’s vast network of small and medium-sized businesses (SMEs), offering an integrated suite of services, including digital payments, bank accounts, credit, foreign exchange (FX), and management tools.

The platform processes over 1 billion transactions monthly, with total payments volume exceeding $22 billion, enabling businesses to digitize their operations and thrive in Africa’s rapidly evolving economy.

With this investment, Visa supports Moniepoint’s mission to empower African businesses, further accelerating its growth and expansion across the continent. Moniepoint’s profitable and scalable business model, alongside its strong operational and financial track record, has positioned it as a transformative force in the African fintech ecosystem.

As Africa’s Fintech landscape continues to evolve rapidly, driven by a dynamic ecosystem and a focus on bridging the financial inclusion gap, Visa has been at the forefront of this transformation, putting its expertise and resources to work in support of the growth of African Fintech startups.

Tosin Eniolorunda, Founder and Group CEO of Moniepoint Inc., said: “We are thrilled to announce Visa’s investment in Moniepoint. Visa’s backing is a strong endorsement of our vision to digitize and support African businesses at scale.

“Together, we aim to deepen financial inclusion, enabling SMEs to access the tools and resources they need to thrive in an increasingly digital economy. Given that about 83% of employment across Africa is in the informal economy, we are very keen to widen access and participation in the formal financial system and drive economic growth across Africa.”

He continued, “Visa’s expertise in global payments and Moniepoint’s proven ability to serve African businesses make this partnership an exciting opportunity in shaping the continent’s economic future even as we pave the way for a more inclusive and dynamic financial ecosystem.

“We are delighted in joining forces with Visa to enhance the digital payment infrastructure, expanding financial services, and fostering innovation in Africa.”

Andrew Torre, Regional President, Central and Eastern Europe, Middle East and Africa at Visa, added: “Moniepoint has built an impressive platform that directly addresses the needs of Africa’s SMEs, a critical segment in enabling economic development.

“By making financial services and digital payments more accessible and efficient, Moniepoint is helping transform how businesses operate in Nigeria and beyond. We are excited to support their next phase of growth and innovation.”

“Visa’s investment in Moniepoint is the latest example of our long-standing commitment to advancing digital economies in Africa. We will enable even the smallest businesses to thrive through innovative payment and software solutions that allow SMEs to scale and open new revenue opportunities, while streamlining their operations.”

Moniepoint has experienced exponential growth since its founding in 2015, with revenues increasing by over 150% CAGR in recent years. The company’s efforts to expand access to financial services align closely with Visa’s mission of enabling individuals and businesses to thrive in the global economy.

Congratulating both parties, the Nigerian Investment Promotion Commission (NIPC) celebrates this strategic investment in Moniepoint, highlighting it as proof of Nigeria’s attractiveness for investors due to its favorable business climate.

Furthermore, the NIPC praised Moniepoint as an exemplar of Nigerian excellence contributing significant value to the global financial ecosystem. The Commission emphasized its commitment to supporting investors and fostering economic cooperation in finance and technology to help Nigeria reach its full economic potential.

This partnership combines Moniepoint’s local expertise and innovative business model with Visa’s global resources and capabilities. Together, Moniepoint and Visa aim to accelerate the digital transformation of African SMEs, driving financial inclusion and long-term economic prosperity.

Visa joins other notable investors including Development Partners International, Google’s Africa Investment Fund, Verod Capital, Lightrock, QED Investors, Novastar Ventures, British International Investment (BII), FMO (the Dutch entrepreneurial development bank), Global Ventures and Endeavor Catalyst in advancing Moniepoint’s mission to create a society where everyone experiences financial happiness.


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