General News
Good News as Scientists Find Ebola Vaccines
A pair of experimental Ebola vaccines that protect monkeys from the fatal disease ravaging West Africa have been developed.
According to a new study, the vaccine is effective for at least five weeks in lab monkeys but requires boosting with an additional vaccine to extend its protection to 10 months.
The findings offer a glimpse of which – if any – of the Ebola vaccines in development will prove effective, and in what form.
Pharmaceutical firms are accelerating their efforts to provide Ebola vaccines and treatments as the worst known outbreak of the virus tears through West Africa, killing more than 2,000 people.
The worst known outbreak of the Ebola virus has ravaged West Africa, killing more than 2,000 people.
The results of the new study suggest, for instance, that a vaccine by pharma giant GlaxoSmithKline (GSK) now being tested on healthy volunteers will protect against Ebola infection in the short term, but may have to be augmented for long-term protection.
The study, published in Nature Medicine, is the first to report that a vaccine regimen produced ‘durable immunity’ against Ebola, protecting four out of four monkeys for 10 months.
The vaccine uses a chimp adenovirus, closely related to a human version that causes upper respiratory tract infections, into which scientists spliced an Ebola gene.
The adenovirus infects cells in a vaccinated animal, causing them to take up the gene and produce Ebola proteins.
That primes the immune system to attack the proteins of Ebola viruses when an infection occurs
The vaccine in the study is similar to competing vaccines being developed by GSK, which began human safety trials last Tuesday, and by Johnson & Johnson (J&J), which aims to start safety trials in early 2015.
A third experimental Ebola vaccine uses a different delivery system, a livestock pathogen called vesicular stomatitis virus (VSV).
A version developed by the Public Health Agency of Canada and licensed to NewLink Genetics is scheduled to be tested for safety in healthy volunteers this fall.
Profectus BioSciences is also developing a VSV vaccine.
In the new study, led by Nancy Sullivan of the National Institute of Allergy and Infectious Diseases (NIAID), researchers sought to see whether a double dose of vaccine in a regimen called ‘prime-boost’ would address two different clinical needs.
One is protecting against Ebola immediately, said Dr Anthony Fauci, NIAID director as when a person is heading to an area with an Ebola outbreak.
In the study, an adenovirus vaccine essentially the same as GSK’s does so: four of four vaccinated macaque monkeys given otherwise lethal doses of Ebola five weeks later survived and had no detectable virus in their blood. All unvaccinated monkeys died within six days.
The other need is to protect someone whose stay in an Ebola zone lasts months.
Here, the adeno vaccine faltered at one dose: when eight vaccinated macaques were exposed to Ebola 10 months later, six died.
With a new group of macaques, however, the scientists followed the initial adeno vaccine eight weeks later with a booster shot using a different carrier virus, called MVA (modified vaccine Ankara) and carrying the same Ebola gene. This time, all four infected monkeys were still protected at 10 months.
The human trial of the GSK vaccine uses a single adenovirus dose: regulators require safety trials to test each element of a regimen separately, said NIAID’s Fauci, so any adverse events can be traced more easily.
GSK also plans to test a two-dose prime-boost version, said spokeswoman Mary Ann Rhyne.
J&J’s Ebola vaccine consists of an adenovirus prime followed by an MVA boost made by Bavarian Nordic.
‘After the boost, protection is not only stronger but also longer-lasting,’ said J&J spokesman Daniel De Schryver.
Thomas Geisbert of the University of Texas Medical Branch works on the VSV-based Ebola vaccine being developed by Profectus.
He questioned the practicality of a two-shot vaccine regimen.
‘You really need a fast-acting single injection vaccine’ for protecting a community during an outbreak or preparing first responders and healthcare workers, he said.
Only VSV vaccines have been shown to protect lab monkeys when given after infection with Ebola, Geisbert said: ‘This makes it so much more useful than any of the other vaccines. For outbreaks, it works fast.’
Nigeria’s Buy Now, Pay Later (BNPL) market is on a fast-growing trajectory and is predicted to be valued $2.61 billion by 2030, up 83% from $1.42 billion in 2024, owing primarily to the rapid emergence of fintechs in the country.
This observation was stated in EnterpriseNGR’s State of Enterprise 2025 report, which focuses on how fintechs are reshaping Nigeria’s business landscape through digital innovations, accessible credit systems, and mobile-first financial tools.
As a credit system, BNPL allows users to stagger payments for products and services, making it a key development driver in Nigeria’s developing digital economy.
From 2021 to 2024, the BNPL experienced a compounded annual growth rate of 23.1%. Fintechs have contributed to the rapid growth by providing a range of flexible loan alternatives for e-commerce, retail, and services, bridging financial gaps for millions of disadvantaged Nigerians.
The report highlights how fintechs have contributed to Nigeria’s flexibility and resiliency by simplifying digital payments, automating invoicing and payroll systems, and democratising credit through platforms such as Renmoney and FairMoney.
The report also shows a significant rise in remittance inflows into Nigeria following the Central Bank of Nigeria’s 2024 policy adjustments.
According to the report, by 2024, Nigeria boasted over 400 licensed digital lenders who extend collateral-free credit to those commonly excluded by banks.
The Nigeria Immigration Service (NIS) strengthened bilateral relations with the Netherlands’ government through an agreement targeted at improving migration governance and border security.
This partnership was confirmed during a meeting at the NIS headquarters in Abuja, which was attended by a Dutch team led by Jurgen Bartelink, Chargé D’Affaires of the Embassy of the Netherlands in Nigeria.
The meeting focused on increasing bilateral migration cooperation and came after the comptroller general of Immigration, Kemi Nandap, paid a working visit to the Netherlands.
Under the agreement, the Dutch government pledged to continue supporting technology-driven solutions targeted at boosting Nigeria’s border control systems and improving migration management.
During the Netherlands Embassy diplomats handed over essential operational tools, such as Edison Software licence keys and the Passport Examination Programme Manual App.
According to NIS spokeswoman ACI Akinsola Akinlabi, “The partnership focuses on enhancing bilateral collaboration on migration management and reviewing ongoing capacity-building efforts.”
Bartelink, Chargé d’Affaires of the Netherlands Embassy in Nigeria, underlined the Netherlands’ commitment to helping Nigeria’s continuing border security and migration reforms.
Also speaking, Rob Bokhoven, head of international affairs, repatriation, and deportation services at the Dutch Ministry of Justice and Security, emphasised the country’s strong bilateral relations and announced plans to share a mobile border software solution with the NIS.
Receiving the equipment, Nandap said the delivery of the gadgets would boost West African country’s border security, significantly improve the service’s document verification border management capabilities and support the implementation of Nigeria’s National Migration Policy.
“The engagement will further reinforce the strategic partnership between Nigeria and the Netherlands advancing shared goals in migration governance, border security and international cooperation,” she added.
Peter Enogb, principal country economist, African Development Bank (AfDB), says the rise in global uncertainty, emanating from increases in global trade tariffs, has slowed Nigeria’s projected growth to 3.2% in 2025.
“Without this level of heightened uncertainty, our projections would probably have been somewhat higher. We’ve reduced our projections for Nigeria. We initially were projecting 3.5% – 3.6% growth in 2025.
“But given the current situation, our models are showing that we’re taking a more cautious approach. So that’s why we produced this and, of course, the main driver is uncertainty in the global economy,” Enogb said.
He said this at the launch of the 2025 Nigeria Country Focus Report (CFR) on Thursday.
AFDB projected that real GDP growth would hit 3.1% in 2026. Following the 2024 consumer price index (CPI) rebasing, with lower weights for food items, the inflation rate is expected to reduce over the medium term to 24.7% in 2025 and 17.3% in 2026.
As imports start to rise over the medium term, the current account is projected to decline to 3.9% of GDP in 2026.
The National Bureau of Statistics (NBS) reported that Nigeria’s headline inflation slowed for the second consecutive month to 22.97% in May. This is down from 24.48% at the start of the year
This is contrary to the World Bank projection that Nigeria’s economy would record steady growth of 3.6% despite the shift in the global trade dynamics.
Joseph Ogebe, head of research and development at Nigerian Economic Summit Group (NESG), also said that global uncertainty had been very high in recent times, resulting from the Trump 2.0 effect.
“And also with the recent war between Israel and the international community, we’ve seen what’s happening to oil prices. Even with the call-off of the war, we’ve seen the effect on oil prices too, which has implications on the fiscal side. So it has implications for the general economy,” he said.
The head of research at NESG said that rather than focusing on just growth, what should be looked at is a strategy called growth with depth.
“Growth with depth means that your growth must be diversified, export-led, productive, and technologically driven,” he said.
Ogebe said that if the Government works towards adopting a strategy of growth with depth, there is a tendency for the government to move towards its goal of achieving a $1 trillion economy by 2030.
The report revealed that the country’s recent policy moves, including fuel subsidy removal, exchange rate unification, and tax reforms, reflect a commitment to long-term transformation.
However, it also pointed out that at about 13%, Nigeria’s tax-to-GDP ratio is among the lowest in West Africa, noting that fiscal reforms are urgent.
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